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Our data suggest that GCLM KO mice have higher capacities for ethanol and acetaldehyde clearance, which may contribute to the protective phenotype

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Iron is not the only metal ion involved in metabolic diseases

Nucleic Acids Res (2009) 37:253948

This allows it to reach tissues that wouldnt normally get much ALA which may explain why higher supplemental doses (like 600mg) can affect nerve health, blood sugar, and oxidative stress in ways your bodys natural supply cant.12 Once you take ALA as a supplement, several factors affect how well your body absorbs and uses it